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Instrumental variable methods for a binary outcome were used to informatively address noncompliance in a randomized trial in surgery

OBJECTIVES: Randomization can be used as an instrumental variable (IV) to account for unmeasured confounding when seeking to assess the impact of noncompliance with treatment allocation in a randomized trial. We present and compare different methods to calculate the treatment effect on a binary outc...

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Detalles Bibliográficos
Autores principales: Cook, Jonathan A., MacLennan, Graeme S., Palmer, Tom, Lois, Noemi, Emsley, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862096/
https://www.ncbi.nlm.nih.gov/pubmed/29157924
http://dx.doi.org/10.1016/j.jclinepi.2017.11.011