STAT3 Gene Silencing by Aptamer-siRNA Chimera as Selective Therapeutic for Glioblastoma

Glioblastoma (GBM) is the most frequent and aggressive primary brain tumor in adults, and despite advances in neuro-oncology, the prognosis for patients remains dismal. The signal transducer and activator of transcription-3 (STAT3) has been reported as a key regulator of the highly aggressive mesenc...

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Detalles Bibliográficos
Autores principales: Esposito, Carla Lucia, Nuzzo, Silvia, Catuogno, Silvia, Romano, Simona, de Nigris, Filomena, de Franciscis, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862137/
https://www.ncbi.nlm.nih.gov/pubmed/29499951
http://dx.doi.org/10.1016/j.omtn.2017.12.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862137/
https://www.ncbi.nlm.nih.gov/pubmed/29499951
http://dx.doi.org/10.1016/j.omtn.2017.12.021

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