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Retrospective review of paediatric case reports of Stevens-Johnson syndrome and toxic epidermal necrolysis with lamotrigine from an international pharmacovigilance database

OBJECTIVES: This study aims to characterise paediatric reports with lamotrigine (LTG) and Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN), and to explore whether potential risk factors can be identified. DESIGN: This is a retrospective review of suspected adverse drug reaction (ADR)...

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Detalles Bibliográficos
Autores principales: Egunsola, Oluwaseun, Star, Kristina, Juhlin, Kristina, Kardaun, Sylvia H, Choonara, Imti, Sammons, Helen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862214/
https://www.ncbi.nlm.nih.gov/pubmed/29637101
http://dx.doi.org/10.1136/bmjpo-2017-000039