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A review of validation strategies for computational drug repositioning

Repositioning of previously approved drugs is a promising methodology because it reduces the cost and duration of the drug development pipeline and reduces the likelihood of unforeseen adverse events. Computational repositioning is especially appealing because of the ability to rapidly screen candid...

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Detalles Bibliográficos
Autores principales: Brown, Adam S, Patel, Chirag J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862266/
https://www.ncbi.nlm.nih.gov/pubmed/27881429
http://dx.doi.org/10.1093/bib/bbw110