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APOBEC3A/B deletion polymorphism and cancer risk

Activity of the apolipoprotein B mRNA editing enzyme, catalytic-polypeptide-like (APOBEC) enzymes has been linked to specific mutational processes in human cancer genomes. A germline APOBEC3A/B deletion polymorphism is associated with APOBEC-dependent mutational signatures, and the deletion allele h...

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Detalles Bibliográficos
Autores principales: Gansmo, Liv B, Romundstad, Paal, Hveem, Kristian, Vatten, Lars, Nik-Zainal, Serena, Lønning, Per Eystein, Knappskog, Stian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862322/
https://www.ncbi.nlm.nih.gov/pubmed/29140415
http://dx.doi.org/10.1093/carcin/bgx131