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APOBEC3A/B deletion polymorphism and cancer risk
Activity of the apolipoprotein B mRNA editing enzyme, catalytic-polypeptide-like (APOBEC) enzymes has been linked to specific mutational processes in human cancer genomes. A germline APOBEC3A/B deletion polymorphism is associated with APOBEC-dependent mutational signatures, and the deletion allele h...
Autores principales: | Gansmo, Liv B, Romundstad, Paal, Hveem, Kristian, Vatten, Lars, Nik-Zainal, Serena, Lønning, Per Eystein, Knappskog, Stian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862322/ https://www.ncbi.nlm.nih.gov/pubmed/29140415 http://dx.doi.org/10.1093/carcin/bgx131 |
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