Indel detection from RNA-seq data: tool evaluation and strategies for accurate detection of actionable mutations

Driver somatic mutations are a hallmark of a tumor that can be used for diagnosis and targeted therapy. Mutations are primarily detected from tumor DNA. As dynamic molecules of gene activities, transcriptome profiling by RNA sequence (RNA-seq) is becoming increasingly popular, which not only measure...

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Detalles Bibliográficos
Autores principales: Sun, Zhifu, Bhagwate, Aditya, Prodduturi, Naresh, Yang, Ping, Kocher, Jean-Pierre A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862335/
https://www.ncbi.nlm.nih.gov/pubmed/27473065
http://dx.doi.org/10.1093/bib/bbw069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862335/
https://www.ncbi.nlm.nih.gov/pubmed/27473065
http://dx.doi.org/10.1093/bib/bbw069

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