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Integrative single-cell omics analyses reveal epigenetic heterogeneity in mouse embryonic stem cells

Embryonic stem cells (ESCs) consist of a population of self-renewing cells displaying extensive phenotypic and functional heterogeneity. Research towards the understanding of the epigenetic mechanisms underlying the heterogeneity among ESCs is still in its initial stage. Key issues, such as how to i...

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Detalles Bibliográficos
Autores principales: Luo, Yanting, He, Jianlin, Xu, Xiguang, Sun, Ming-an, Wu, Xiaowei, Lu, Xuemei, Xie, Hehuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862410/
https://www.ncbi.nlm.nih.gov/pubmed/29561833
http://dx.doi.org/10.1371/journal.pcbi.1006034