The dual CCR2/CCR5 chemokine receptor antagonist Cenicriviroc reduces macrophage infiltration and disease severity in Duchenne muscular dystrophy (Dmd(mdx-4Cv)) mice

Duchenne muscular dystrophy (DMD) is characterized by progressive muscle weakness which is ultimately fatal, most often due to involvement of the diaphragm. Macrophage infiltration of dystrophic muscles has been strongly linked to muscle damage and fibrosis in DMD. We hypothesized that cenicriviroc...

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Detalles Bibliográficos
Autores principales: Liang, Feng, Giordano, Christian, Shang, Dong, Li, Qian, Petrof, Basil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862483/
https://www.ncbi.nlm.nih.gov/pubmed/29561896
http://dx.doi.org/10.1371/journal.pone.0194421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862483/
https://www.ncbi.nlm.nih.gov/pubmed/29561896
http://dx.doi.org/10.1371/journal.pone.0194421

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