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ChromoTrace: Computational reconstruction of 3D chromosome configurations for super-resolution microscopy

The 3D structure of chromatin plays a key role in genome function, including gene expression, DNA replication, chromosome segregation, and DNA repair. Furthermore the location of genomic loci within the nucleus, especially relative to each other and nuclear structures such as the nuclear envelope an...

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Detalles Bibliográficos
Autores principales: Barton, Carl, Morganella, Sandro, Ødegård-Fougner, Øyvind, Alexander, Stephanie, Ries, Jonas, Fitzgerald, Tomas, Ellenberg, Jan, Birney, Ewan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862484/
https://www.ncbi.nlm.nih.gov/pubmed/29522506
http://dx.doi.org/10.1371/journal.pcbi.1006002