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ChromoTrace: Computational reconstruction of 3D chromosome configurations for super-resolution microscopy
The 3D structure of chromatin plays a key role in genome function, including gene expression, DNA replication, chromosome segregation, and DNA repair. Furthermore the location of genomic loci within the nucleus, especially relative to each other and nuclear structures such as the nuclear envelope an...
Autores principales: | Barton, Carl, Morganella, Sandro, Ødegård-Fougner, Øyvind, Alexander, Stephanie, Ries, Jonas, Fitzgerald, Tomas, Ellenberg, Jan, Birney, Ewan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862484/ https://www.ncbi.nlm.nih.gov/pubmed/29522506 http://dx.doi.org/10.1371/journal.pcbi.1006002 |
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