Broken replication forks trigger heritable DNA breaks in the terminus of a circular chromosome

It was recently reported that the recBC mutants of Escherichia coli, deficient for DNA double-strand break (DSB) repair, have a decreased copy number of their terminus region. We previously showed that this deficit resulted from DNA loss after post-replicative breakage of one of the two sister-chrom...

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Detalles Bibliográficos
Autores principales: Sinha, Anurag Kumar, Possoz, Christophe, Durand, Adeline, Desfontaines, Jean-Michel, Barre, François-Xavier, Leach, David R. F., Michel, Bénédicte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862497/
https://www.ncbi.nlm.nih.gov/pubmed/29522563
http://dx.doi.org/10.1371/journal.pgen.1007256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862497/
https://www.ncbi.nlm.nih.gov/pubmed/29522563
http://dx.doi.org/10.1371/journal.pgen.1007256

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