Morphogenetic defects underlie Superior Coloboma, a newly identified closure disorder of the dorsal eye

The eye primordium arises as a lateral outgrowth of the forebrain, with a transient fissure on the inferior side of the optic cup providing an entry point for developing blood vessels. Incomplete closure of the inferior ocular fissure results in coloboma, a disease characterized by gaps in the infer...

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Detalles Bibliográficos
Autores principales: Hocking, Jennifer C., Famulski, Jakub K., Yoon, Kevin H., Widen, Sonya A., Bernstein, Cassidy S., Koch, Sophie, Weiss, Omri, Agarwala, Seema, Inbal, Adi, Lehmann, Ordan J., Waskiewicz, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862500/
https://www.ncbi.nlm.nih.gov/pubmed/29522511
http://dx.doi.org/10.1371/journal.pgen.1007246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862500/
https://www.ncbi.nlm.nih.gov/pubmed/29522511
http://dx.doi.org/10.1371/journal.pgen.1007246

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