Transient external force induces phenotypic reversion of malignant epithelial structures via nitric oxide signaling

Non-malignant breast epithelial cells cultured in three-dimensional laminin-rich extracellular matrix (lrECM) form well organized, growth-arrested acini, whereas malignant cells form continuously growing disorganized structures. While the mechanical properties of the microenvironment have been shown...

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Detalles Bibliográficos
Autores principales: Ricca, Benjamin L, Venugopalan, Gautham, Furuta, Saori, Tanner, Kandice, Orellana, Walter A, Reber, Clay D, Brownfield, Douglas G, Bissell, Mina J, Fletcher, Daniel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862525/
https://www.ncbi.nlm.nih.gov/pubmed/29560858
http://dx.doi.org/10.7554/eLife.26161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862525/
https://www.ncbi.nlm.nih.gov/pubmed/29560858
http://dx.doi.org/10.7554/eLife.26161

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