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Transient external force induces phenotypic reversion of malignant epithelial structures via nitric oxide signaling

Non-malignant breast epithelial cells cultured in three-dimensional laminin-rich extracellular matrix (lrECM) form well organized, growth-arrested acini, whereas malignant cells form continuously growing disorganized structures. While the mechanical properties of the microenvironment have been shown...

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Detalles Bibliográficos
Autores principales:	Ricca, Benjamin L, Venugopalan, Gautham, Furuta, Saori, Tanner, Kandice, Orellana, Walter A, Reber, Clay D, Brownfield, Douglas G, Bissell, Mina J, Fletcher, Daniel A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862525/ https://www.ncbi.nlm.nih.gov/pubmed/29560858 http://dx.doi.org/10.7554/eLife.26161

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