A switch in transcription and cell fate governs the onset of an epigenetically-deregulated tumor in Drosophila

Tumor initiation is often linked to a loss of cellular identity. Transcriptional programs determining cellular identity are preserved by epigenetically-acting chromatin factors. Although such regulators are among the most frequently mutated genes in cancer, it is not well understood how an abnormal...

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Detalles Bibliográficos
Autores principales: Torres, Joana, Monti, Remo, Moore, Ariane L, Seimiya, Makiko, Jiang, Yanrui, Beerenwinkel, Niko, Beisel, Christian, Beira, Jorge V, Paro, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862528/
https://www.ncbi.nlm.nih.gov/pubmed/29560857
http://dx.doi.org/10.7554/eLife.32697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862528/
https://www.ncbi.nlm.nih.gov/pubmed/29560857
http://dx.doi.org/10.7554/eLife.32697

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