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A switch in transcription and cell fate governs the onset of an epigenetically-deregulated tumor in Drosophila
Tumor initiation is often linked to a loss of cellular identity. Transcriptional programs determining cellular identity are preserved by epigenetically-acting chromatin factors. Although such regulators are among the most frequently mutated genes in cancer, it is not well understood how an abnormal...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862528/ https://www.ncbi.nlm.nih.gov/pubmed/29560857 http://dx.doi.org/10.7554/eLife.32697 |