IL-21 modulates memory and exhaustion phenotype of T-cells in a fatty acid oxidation-dependent manner

T-cell-based therapies represent a promising strategy for cancer treatment. In this context, cytokines are discussed as a bona fide instrument for fine-tuning T- cell biology. One promising candidate is the pleiotropic interleukin-21 (IL-21) with only little being known regarding its direct effects...

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Detalles Bibliográficos
Autores principales: Loschinski, Romy, Böttcher, Martin, Stoll, Andrej, Bruns, Heiko, Mackensen, Andreas, Mougiakakos, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862566/
https://www.ncbi.nlm.nih.gov/pubmed/29568345
http://dx.doi.org/10.18632/oncotarget.24442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862566/
https://www.ncbi.nlm.nih.gov/pubmed/29568345
http://dx.doi.org/10.18632/oncotarget.24442

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