Molecular profiling of ALDH1(+) colorectal cancer stem cells reveals preferential activation of MAPK, FAK, and oxidative stress pro-survival signalling pathways

Tumour heterogeneity leads to variable clinical response and inaccurate diagnostic and prognostic assessment. Cancer stem cells (CSCs) represent a subpopulation responsible for invasion, metastasis, therapeutic resistance, and recurrence in many human cancer types. However, the true identity of colo...

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Detalles Bibliográficos
Autores principales: Vishnubalaji, Radhakrishnan, Manikandan, Muthurangan, Fahad, Mohamed, Hamam, Rimi, Alfayez, Musaad, Kassem, Moustapha, Aldahmash, Abdullah, Alajez, Nehad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862598/
https://www.ncbi.nlm.nih.gov/pubmed/29568377
http://dx.doi.org/10.18632/oncotarget.24420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862598/
https://www.ncbi.nlm.nih.gov/pubmed/29568377
http://dx.doi.org/10.18632/oncotarget.24420

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