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Molecular profiling of ALDH1(+) colorectal cancer stem cells reveals preferential activation of MAPK, FAK, and oxidative stress pro-survival signalling pathways

Tumour heterogeneity leads to variable clinical response and inaccurate diagnostic and prognostic assessment. Cancer stem cells (CSCs) represent a subpopulation responsible for invasion, metastasis, therapeutic resistance, and recurrence in many human cancer types. However, the true identity of colo...

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Detalles Bibliográficos
Autores principales:	Vishnubalaji, Radhakrishnan, Manikandan, Muthurangan, Fahad, Mohamed, Hamam, Rimi, Alfayez, Musaad, Kassem, Moustapha, Aldahmash, Abdullah, Alajez, Nehad M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862598/ https://www.ncbi.nlm.nih.gov/pubmed/29568377 http://dx.doi.org/10.18632/oncotarget.24420

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