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The development of CAR design for tumor CAR-T cell therapy

In recent years, the chimeric antigen receptor modified T cells (Chimeric antigen receptor T cells, CAR-T) immunotherapy has developed rapidly, which has been considered the most promising therapy. Efforts to enhance the efficacy of CAR-based anti-tumor therapy have been made, such as the improvemen...

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Detalles Bibliográficos
Autores principales: Xu, Dandan, Jin, Guoliang, Chai, Dafei, Zhou, Xiaowan, Gu, Weiyu, Chong, Yanyun, Song, Jingyuan, Zheng, Junnian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862632/
https://www.ncbi.nlm.nih.gov/pubmed/29568411
http://dx.doi.org/10.18632/oncotarget.24179