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RNA-dependent chromatin targeting of TET2 for endogenous retrovirus control in pluripotent stem cells
Ten-eleven translocation (TET) proteins play key roles in regulating the methylation status of DNA through oxidizing methylcytosines (5mC), generating 5-hydroxymethylcytosines (5hmC) that can both serve as stable epigenetic marks and participate in active demethylation. Unlike the other TET-family m...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862756/ https://www.ncbi.nlm.nih.gov/pubmed/29483655 http://dx.doi.org/10.1038/s41588-018-0060-9 |