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Evaluation of the Efficacy and Cross-Protective Immunity of Live-Attenuated Chimeric PCV1-2b Vaccine Against PCV2b and PCV2d Subtype Challenge in Pigs

Porcine circovirus type 2 (PCV2) commercial vaccines are either inactivated PCV2 isolates or subunit vaccine based on the Cap protein of PCV2. Currently, no live-attenuated vaccines are yet available. Although the predominant circulating subtype worldwide is PCV2b, the emerging PCV2d subtype is also...

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Detalles Bibliográficos
Autores principales: Huan, Changchao, Fan, Mingyu, Cheng, Qingru, Wang, Xiaobo, Gao, Qingqing, Wang, Wanbin, Gao, Song, Liu, Xiufan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862802/
https://www.ncbi.nlm.nih.gov/pubmed/29599761
http://dx.doi.org/10.3389/fmicb.2018.00455