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Ucma/GRP inhibits phosphate-induced vascular smooth muscle cell calcification via SMAD-dependent BMP signalling

Vascular calcification (VC) is the process of deposition of calcium phosphate crystals in the blood vessel wall, with a central role for vascular smooth muscle cells (VSMCs). VC is highly prevalent in chronic kidney disease (CKD) patients and thought, in part, to be induced by phosphate imbalance. T...

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Detalles Bibliográficos
Autores principales: Willems, Brecht A., Furmanik, Malgorzata, Caron, Marjolein M. J., Chatrou, Martijn L. L., Kusters, Dennis H. M., Welting, Tim J. M., Stock, Michael, Rafael, Marta S., Viegas, Carla S. B., Simes, Dina C., Vermeer, Cees, Reutelingsperger, Chris P. M., Schurgers, Leon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862840/
https://www.ncbi.nlm.nih.gov/pubmed/29563538
http://dx.doi.org/10.1038/s41598-018-23353-y