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Ucma/GRP inhibits phosphate-induced vascular smooth muscle cell calcification via SMAD-dependent BMP signalling
Vascular calcification (VC) is the process of deposition of calcium phosphate crystals in the blood vessel wall, with a central role for vascular smooth muscle cells (VSMCs). VC is highly prevalent in chronic kidney disease (CKD) patients and thought, in part, to be induced by phosphate imbalance. T...
Autores principales: | Willems, Brecht A., Furmanik, Malgorzata, Caron, Marjolein M. J., Chatrou, Martijn L. L., Kusters, Dennis H. M., Welting, Tim J. M., Stock, Michael, Rafael, Marta S., Viegas, Carla S. B., Simes, Dina C., Vermeer, Cees, Reutelingsperger, Chris P. M., Schurgers, Leon J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862840/ https://www.ncbi.nlm.nih.gov/pubmed/29563538 http://dx.doi.org/10.1038/s41598-018-23353-y |
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