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CISNE: An accurate description of dose-effect and synergism in combination therapies

The precise determination of dose-effect curves and the combination effect of drugs is of crucial importance in the development of new therapies for the most dreadful diseases. We have found that the current implementations of the theory of Chou et al. are not accurate enough in some circumstances a...

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Detalles Bibliográficos
Autores principales: García-Fuente, Amador, Vázquez, Fernando, Viéitez, José M., García Alonso, Francisco J., Martín, José I., Ferrer, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862869/
https://www.ncbi.nlm.nih.gov/pubmed/29563526
http://dx.doi.org/10.1038/s41598-018-23321-6