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CISNE: An accurate description of dose-effect and synergism in combination therapies
The precise determination of dose-effect curves and the combination effect of drugs is of crucial importance in the development of new therapies for the most dreadful diseases. We have found that the current implementations of the theory of Chou et al. are not accurate enough in some circumstances a...
Autores principales: | García-Fuente, Amador, Vázquez, Fernando, Viéitez, José M., García Alonso, Francisco J., Martín, José I., Ferrer, Jaime |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862869/ https://www.ncbi.nlm.nih.gov/pubmed/29563526 http://dx.doi.org/10.1038/s41598-018-23321-6 |
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