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Dual role of E-cadherin in the regulation of invasive collective migration of mammary carcinoma cells

In this article, we explore a non-canonical form of collective cell migration, displayed by the metastatic murine mammary carcinoma cell line 4T1. We show here that in sparsely plated 4T1 cells, E-cadherin levels are moderately reduced (~50%), leading to the development of collective migration, wher...

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Detalles Bibliográficos
Autores principales: Elisha, Yair, Kalchenko, Vyacheslav, Kuznetsov, Yuri, Geiger, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862898/
https://www.ncbi.nlm.nih.gov/pubmed/29563585
http://dx.doi.org/10.1038/s41598-018-22940-3