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Flexible pseudotyping of retrovirus using recombinase-mediated cassette exchange
OBJECTIVE: Develop an engineered cell line containing two flexible gene expression systems enabling the continuous production of tailor-made recombinant gammaretrovirus with predictable productivities through targeted integration. RESULTS: Dual-FLEX cells (dFLEX) contain two independent recombinase-...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862940/ https://www.ncbi.nlm.nih.gov/pubmed/29353442 http://dx.doi.org/10.1007/s10529-018-2515-6 |