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Neuroprotective effect of dexmedetomidine in a murine model of traumatic brain injury

No FDA approved pharmacological therapy is available that would reduce cell death following traumatic brain injury (TBI). Dexmedetomidine (Dex) is a highly selective agonist of alpha-2 adrenergic receptors and has demonstrated neuroprotective effects in hippocampal slice cultures undergoing direct i...

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Detalles Bibliográficos
Autores principales: Wu, Jin, Vogel, Todd, Gao, Xiang, Lin, Bin, Kulwin, Charles, Chen, Jinhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862953/
https://www.ncbi.nlm.nih.gov/pubmed/29563509
http://dx.doi.org/10.1038/s41598-018-23003-3