Environmental and Genetic Variables Influencing Mitochondrial Health and Parkinson's Disease Penetrance

There is strong evidence that impairment of mitochondrial function plays a key role in the pathogenesis of PD. The two key PD genes related to mitochondrial function are Parkin (PARK2) and PINK1 (PARK6), and also mutations in several other PD genes, including SNCA, LRRK2, DJ1, CHCHD2, and POLG, have...

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Detalles Bibliográficos
Autores principales: Zanon, Alessandra, Pramstaller, Peter P., Hicks, Andrew A., Pichler, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863306/
https://www.ncbi.nlm.nih.gov/pubmed/29707191
http://dx.doi.org/10.1155/2018/8684906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863306/
https://www.ncbi.nlm.nih.gov/pubmed/29707191
http://dx.doi.org/10.1155/2018/8684906

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