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Characterization of association of human mitochondrial lysyl-tRNA synthetase with HIV-1 Pol and tRNA(3)(Lys)

BACKGROUND: An important step in human immunodeficiency virus type 1 (HIV-1) replication is the packaging of tRNA(3)(Lys) from the host cell, which plays the role of primer RNA in the process of initiation of reverse transcription. The viral GagPol polyprotein precursor, and the human mitochondrial...

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Detalles Bibliográficos
Autores principales: Khoder-Agha, Fawzi, Dias, José M., Comisso, Martine, Mirande, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863373/
https://www.ncbi.nlm.nih.gov/pubmed/29562886
http://dx.doi.org/10.1186/s12858-018-0092-x