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Gas5 is an essential lncRNA regulator for self-renewal and pluripotency of mouse embryonic stem cells and induced pluripotent stem cells

BACKGROUND: The regulatory role of long noncoding RNAs (lncRNAs) have been partially proved in embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). METHODS: In the current study, we investigated mouse ESC (mESC) self-renewal, differentiation, and proliferation in vitro by knocking...

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Detalles Bibliográficos
Autores principales: Tu, Jiajie, Tian, Geng, Cheung, Hoi-Hung, Wei, Wei, Lee, Tin-lap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863440/
https://www.ncbi.nlm.nih.gov/pubmed/29562912
http://dx.doi.org/10.1186/s13287-018-0813-5