Epistructured catechins, EGCG and EC facilitate apoptosis induction through targeting de novo lipogenesis pathway in HepG2 cells

BACKGROUND: Abnormally high expression of the mammalian de novo lipogenesis (DNL) pathway in various cancer cells promotes cell over-proliferation and resistance to apoptosis. Inhibition of key enzymes in the DNL pathway, namely, ATP citrate lyase, acetyl-CoA carboxylase, and fatty acid synthase (FA...

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Detalles Bibliográficos
Autores principales: Khiewkamrop, Phuriwat, Phunsomboon, Pattamaphron, Richert, Lysiane, Pekthong, Dumrongsak, Srisawang, Piyarat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863485/
https://www.ncbi.nlm.nih.gov/pubmed/29588626
http://dx.doi.org/10.1186/s12935-018-0539-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863485/
https://www.ncbi.nlm.nih.gov/pubmed/29588626
http://dx.doi.org/10.1186/s12935-018-0539-6

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