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Herpesviruses in the Activated Phosphatidylinositol-3-Kinase-δ Syndrome
The phosphatidylinositol-3-kinase (PI3K)/Akt pathway is important for multiple stages of herpesvirus replication including virus entry, replication, latency, and reactivation. Recently, patients with gain-of-function mutations in the p110δ-catalytic subunit of PI3K or in the p85-regulatory subunit o...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863522/ https://www.ncbi.nlm.nih.gov/pubmed/29599765 http://dx.doi.org/10.3389/fimmu.2018.00237 |