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Herpesviruses in the Activated Phosphatidylinositol-3-Kinase-δ Syndrome

The phosphatidylinositol-3-kinase (PI3K)/Akt pathway is important for multiple stages of herpesvirus replication including virus entry, replication, latency, and reactivation. Recently, patients with gain-of-function mutations in the p110δ-catalytic subunit of PI3K or in the p85-regulatory subunit o...

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Detalles Bibliográficos
Autor principal: Cohen, Jeffrey I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863522/
https://www.ncbi.nlm.nih.gov/pubmed/29599765
http://dx.doi.org/10.3389/fimmu.2018.00237

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