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Triple Function of Synaptotagmin 7 Ensures Efficiency of High-Frequency Transmission at Central GABAergic Synapses

Synaptotagmin 7 (Syt7) is thought to be a Ca(2+) sensor that mediates asynchronous transmitter release and facilitation at synapses. However, Syt7 is strongly expressed in fast-spiking, parvalbumin-expressing GABAergic interneurons, and the output synapses of these neurons produce only minimal async...

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Detalles Bibliográficos
Autores principales: Chen, Chong, Satterfield, Rachel, Young, Samuel M., Jonas, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863544/
https://www.ncbi.nlm.nih.gov/pubmed/29166601
http://dx.doi.org/10.1016/j.celrep.2017.10.122