Synthesis of poly(1,2-glycerol carbonate)–paclitaxel conjugates and their utility as a single high-dose replacement for multi-dose treatment regimens in peritoneal cancer

Current chemotherapeutic dosing strategies are limited by the toxicity of anticancer agents and therefore rely on multiple low-dose administrations. As an alternative, we describe a novel sustained-release, biodegradable polymeric nanocarrier as a single administration replacement of multi-dose pacl...

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Detalles Bibliográficos
Autores principales: Ekladious, Iriny, Liu, Rong, Zhang, Heng, Foil, Daniel H., Todd, Daniel A., Graf, Tyler N., Padera, Robert F., Oberlies, Nicholas H., Colson, Yolonda L., Grinstaff, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863611/
https://www.ncbi.nlm.nih.gov/pubmed/29619192
http://dx.doi.org/10.1039/c7sc03501b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863611/
https://www.ncbi.nlm.nih.gov/pubmed/29619192
http://dx.doi.org/10.1039/c7sc03501b

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