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Preferential binding of fullerene and fullerenol with the N-terminal and middle regions of amyloid beta peptide: an in silico investigation

Amyloid beta (Aβ) deposits are implicated in the pathogenesis of debilitating neurodegenerative disorders such as Alzheimer’s disease. In the present study, the interactions of carbon-based nanoparticles (NPs) such as fullerene and fullerenol having different surface chemistry with Aβ were investiga...

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Detalles Bibliográficos
Autores principales: Pandya, Vishal, Baweja, Lokesh, Dhawan, Alok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863620/
https://www.ncbi.nlm.nih.gov/pubmed/29593399
http://dx.doi.org/10.2147/IJN.S125011