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Completing sparse and disconnected protein-protein network by deep learning

BACKGROUND: Protein-protein interaction (PPI) prediction remains a central task in systems biology to achieve a better and holistic understanding of cellular and intracellular processes. Recently, an increasing number of computational methods have shifted from pair-wise prediction to network level p...

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Detalles Bibliográficos
Autores principales: Huang, Lei, Liao, Li, Wu, Cathy H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863833/
https://www.ncbi.nlm.nih.gov/pubmed/29566671
http://dx.doi.org/10.1186/s12859-018-2112-7