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Murine breast cancer feed arteries are thin-walled with reduced α(1A)-adrenoceptor expression and attenuated sympathetic vasocontraction

BACKGROUND: Perfusion of breast cancer tissue limits oxygen availability and metabolism but angiogenesis inhibitors have hitherto been unsuccessful for breast cancer therapy. In order to identify abnormalities and possible therapeutic targets in mature cancer arteries, we here characterize the struc...

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Detalles Bibliográficos
Autores principales: Froelunde, Anne Sofie, Ohlenbusch, Marit, Hansen, Kristoffer B., Jessen, Nicolai, Kim, Sukhan, Boedtkjer, Ebbe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863844/
https://www.ncbi.nlm.nih.gov/pubmed/29566737
http://dx.doi.org/10.1186/s13058-018-0952-8