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Integrative genomics identifies new genes associated with severe COPD and emphysema

BACKGROUND: Genome-wide association studies have identified several genetic risk loci for severe chronic obstructive pulmonary disease (COPD) and emphysema. However, these studies do not fully explain disease heritability and in most cases, fail to implicate specific genes. Integrative methods that...

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Detalles Bibliográficos
Autores principales: Sakornsakolpat, Phuwanat, Morrow, Jarrett D., Castaldi, Peter J., Hersh, Craig P., Bossé, Yohan, Silverman, Edwin K., Manichaikul, Ani, Cho, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863845/
https://www.ncbi.nlm.nih.gov/pubmed/29566699
http://dx.doi.org/10.1186/s12931-018-0744-9