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Integrative genomics identifies new genes associated with severe COPD and emphysema
BACKGROUND: Genome-wide association studies have identified several genetic risk loci for severe chronic obstructive pulmonary disease (COPD) and emphysema. However, these studies do not fully explain disease heritability and in most cases, fail to implicate specific genes. Integrative methods that...
Autores principales: | Sakornsakolpat, Phuwanat, Morrow, Jarrett D., Castaldi, Peter J., Hersh, Craig P., Bossé, Yohan, Silverman, Edwin K., Manichaikul, Ani, Cho, Michael H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863845/ https://www.ncbi.nlm.nih.gov/pubmed/29566699 http://dx.doi.org/10.1186/s12931-018-0744-9 |
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