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Activation gating in HCN2 channels

Hyperpolarization-activated cyclic nucleotide-modulated (HCN) channels control electrical rhythmicity in specialized brain and heart cells. We quantitatively analysed voltage-dependent activation of homotetrameric HCN2 channels and its modulation by the second messenger cAMP using global fits of hid...

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Detalles Bibliográficos
Autores principales: Hummert, Sabine, Thon, Susanne, Eick, Thomas, Schmauder, Ralf, Schulz, Eckhard, Benndorf, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863937/
https://www.ncbi.nlm.nih.gov/pubmed/29565972
http://dx.doi.org/10.1371/journal.pcbi.1006045