Cargando…

CCAAT-enhancer binding protein-α (C/EBPα) and hepatocyte nuclear factor 4α (HNF4α) regulate expression of the human fructose-1,6-bisphosphatase 1 (FBP1) gene in human hepatocellular carcinoma HepG2 cells

Fructose-1,6-bisphosphatase (FBP1) plays an essential role in gluconeogenesis. Here we report that the human FBP1 gene is regulated by two liver-enriched transcription factors, CCAAT-enhancer binding protein-α (C/EBPα) and hepatocyte nuclear factor 4α (HNF4α) in human hepatoma HepG2 cells. C/EBPα re...

Descripción completa

Detalles Bibliográficos
Autores principales: Wattanavanitchakorn, Siriluck, Rojvirat, Pinnara, Chavalit, Tanit, MacDonald, Michael J., Jitrapakdee, Sarawut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863999/
https://www.ncbi.nlm.nih.gov/pubmed/29566023
http://dx.doi.org/10.1371/journal.pone.0194252