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Fluid shear stress impacts ovarian cancer cell viability, subcellular organization, and promotes genomic instability

Ovarian cancer cells are exposed to physical stress in the peritoneal cavity during both tumor growth and dissemination. Ascites build-up in metastatic ovarian cancer further increases the exposure to fluid shear stress. Here, we used a murine, in vitro ovarian cancer progression model in parallel w...

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Detalles Bibliográficos
Autores principales: Hyler, Alexandra R., Baudoin, Nicolaas C., Brown, Megan S., Stremler, Mark A., Cimini, Daniela, Davalos, Rafael V., Schmelz, Eva M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864000/
https://www.ncbi.nlm.nih.gov/pubmed/29566010
http://dx.doi.org/10.1371/journal.pone.0194170