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Fluid shear stress impacts ovarian cancer cell viability, subcellular organization, and promotes genomic instability
Ovarian cancer cells are exposed to physical stress in the peritoneal cavity during both tumor growth and dissemination. Ascites build-up in metastatic ovarian cancer further increases the exposure to fluid shear stress. Here, we used a murine, in vitro ovarian cancer progression model in parallel w...
Autores principales: | Hyler, Alexandra R., Baudoin, Nicolaas C., Brown, Megan S., Stremler, Mark A., Cimini, Daniela, Davalos, Rafael V., Schmelz, Eva M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864000/ https://www.ncbi.nlm.nih.gov/pubmed/29566010 http://dx.doi.org/10.1371/journal.pone.0194170 |
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