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Rats deficient C-type natriuretic peptide suffer from impaired skeletal growth without early death

We have previously investigated the physiological role of C-type natriuretic peptide (CNP) on endochondral bone growth, mainly with mutant mouse models deficient in CNP, and reported that CNP is indispensable for physiological endochondral bone growth in mice. However, the survival rate of CNP knock...

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Detalles Bibliográficos
Autores principales: Fujii, Toshihito, Hirota, Keisho, Yasoda, Akihiro, Takizawa, Akiko, Morozumi, Naomi, Nakamura, Ryuichi, Yotsumoto, Takafumi, Kondo, Eri, Yamashita, Yui, Sakane, Yoriko, Kanai, Yugo, Ueda, Yohei, Yamauchi, Ichiro, Yamanaka, Shigeki, Nakao, Kazumasa, Kuwahara, Koichiro, Jindo, Toshimasa, Furuya, Mayumi, Mashimo, Tomoji, Inagaki, Nobuya, Serikawa, Tadao, Nakao, Kazuwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864047/
https://www.ncbi.nlm.nih.gov/pubmed/29566041
http://dx.doi.org/10.1371/journal.pone.0194812