The GAG-specific branched peptide NT4 reduces angiogenesis and invasiveness of tumor cells

Heparan sulfate proteoglycans, HSPGs, modulate major transformations of cancer cells, leading to tumor growth, invasion and metastasis. HSPGs also regulate neo-angiogenesis which prompts cancer progression and metastatic spread. A different aspect of heparin and analogs is their prominent role in th...

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Detalles Bibliográficos
Autores principales: Bracci, Luisa, Mandarini, Elisabetta, Brunetti, Jlenia, Depau, Lorenzo, Pini, Alessandro, Terzuoli, Lucia, Scali, Silvia, Falciani, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864057/
https://www.ncbi.nlm.nih.gov/pubmed/29566097
http://dx.doi.org/10.1371/journal.pone.0194744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864057/
https://www.ncbi.nlm.nih.gov/pubmed/29566097
http://dx.doi.org/10.1371/journal.pone.0194744

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