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The Plasmodium falciparum transcriptome in severe malaria reveals altered expression of genes involved in important processes including surface antigen–encoding var genes

Within the human host, the malaria parasite Plasmodium falciparum is exposed to multiple selection pressures. The host environment changes dramatically in severe malaria, but the extent to which the parasite responds to—or is selected by—this environment remains unclear. From previous studies, the p...

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Detalles Bibliográficos
Autores principales: Tonkin-Hill, Gerry Q., Trianty, Leily, Noviyanti, Rintis, Nguyen, Hanh H. T., Sebayang, Boni F., Lampah, Daniel A., Marfurt, Jutta, Cobbold, Simon A., Rambhatla, Janavi S., McConville, Malcolm J., Rogerson, Stephen J., Brown, Graham V., Day, Karen P., Price, Ric N., Anstey, Nicholas M., Papenfuss, Anthony T., Duffy, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864071/
https://www.ncbi.nlm.nih.gov/pubmed/29529020
http://dx.doi.org/10.1371/journal.pbio.2004328